While is copes quite well with the compression ratio, there appears to be no other benefit, unless you had a turbo engine.
However on the down side, it uses a massive amount of fuel compared to conventional fuels, this means larger fuel lines, pressure reg etc. The blow by has a strong tendency to dilute the engine oil. The fuel being an alcohol type is hygroscopic in that it absorbs moisture. You can end up with a catch can that distils its own alcohol in it. Also like Methanol the car can be hard to start cold. While V8 tourers use the fuel they do so for more political reasons.