In the end it all comes down to personal preference. Vinnie is right about the risk of the bass becoming too boomy with 6x9s and a sub and many will be satisfied with a sub powered from 2 channels bridged. If you're not fussed with the bass then just get a 4 channel amp and power all four speakers, then grab a sub from a shop that is selling u the amp and just try it bridged to see which sound you prefer.
The bass also depends on the quality of ur doors and soundproofing. I've been in volvos where factory sound deadening is top notch and the bass coming out of their stock 6x9s is way better than some accords running 12" subs that forces compressed air into your nose with every bass drum beat.
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